Rams vs. 49ers Fantasy Lineup Advice for DraftKings, FanDuel

When the Rams and 49ers clash on Thursday Night Football (TNF) in Week 15, daily fantasy football players on DraftKings and FanDuel can capitalize on high-scoring trends. Both teams have surpassed 20 points in their last three meetings, with two of those matchups exceeding 50 points. With stars like Puka Nacua, George Kittle, and Brock Purdy in action, these players could shine in NFL DFS lineups. Here’s expert Jimmie Kaylor’s take on crafting the perfect lineup.

Top Rams vs. 49ers NFL DFS Picks

1. Puka Nacua – WR, Rams

Puka Nacua is a must-have for TNF NFL DFS lineups, emerging as the Rams’ offensive leader.

• Stats to Note:
  • 12 receptions, 162 yards, and 1 TD on 14 targets last week.
  • Averaging 10.2 targets per game since Week 10.
• Matchup History:
  • 15 receptions for 147 yards in his first career game against the 49ers.
  • Scored a touchdown in their second meeting last season.

Nacua’s consistency and target share make him a top choice, especially with Cooper Kupp drawing extra defensive attention.

2. George Kittle – TE, 49ers

George Kittle has stepped up as a key offensive weapon for the 49ers, especially with Deebo Samuel struggling to hit his usual production levels.

• Recent Performance:
  • Season-high 151 yards on six receptions last week.
  • Averaging 102 receiving yards per game over his last five outings (excluding one snow game).
• Fantasy Football Rankings:
  • TE2 overall this season.
  • TE1 in points per game in recent weeks.

With the Rams allowing four or more receptions to opposing tight ends in three of their last four games, Kittle is a high-upside pick for TNF.

Key Strategy: Stacks and Value Players

Consider These NFL DFS Stacks:

• Brock Purdy + George Kittle + Brandon Aiyuk

  • Purdy’s ability to spread the ball, combined with Kittle’s reliability and Aiyuk’s big-play potential, can provide a high-ceiling stack.

• Matthew Stafford + Puka Nacua + Kyren Williams

  • Stafford’s connection with Nacua has been solid, and Williams adds versatility with his rushing and receiving skills.

Under-the-Radar Value Picks

Kaylor suggests keeping an eye on lesser-known players who could deliver significant returns, particularly those benefiting from injuries or favorable matchups. One undervalued player could make the difference in your lineup.

Why Trust Jimmie Kaylor’s Advice?

• Proven Track Record:
  • Winner of DraftKings’ NFL Showdown Thursday Kickoff Millionaire Contest in 2022.
  • Multiple five-figure DFS tournament wins.
• Unique Insights:
  • Former college and NFL player with nearly a decade of coverage as a Pro Football Writers of America member.

Kaylor has consistently hit on breakout performances, including Travis Kelce’s four-touchdown game in 2022 and Ja’Marr Chase’s 192-yard explosion in Week 5 of 2023.

How to Build Your Rams vs. 49ers TNF Lineup

Jimmie Kaylor has identified another undervalued sleeper poised for a breakout in this matchup. To access his full lineup recommendations, including rankings, stacks, and player pool insights, head to SportsLine for expert picks.

Don’t miss out on an edge for DraftKings and FanDuel. Visit SportsLine now to unlock Kaylor’s top plays and build a winning NFL DFS lineup for Rams vs. 49ers.